Dental Pulp Stem Cells Progress From Discovery to Clinical Application

ABSTRACT

Dental Pulp Stem Cells: From Discovery to Clinical Application.
J Endod. 2020 Sep;46(9S):S46-S55. doi: 10.1016/j.joen.2020.06.027.

Sui B, Wu D, Xiang L, Fu Y, Kou X, Shi S.

Author information
Department of Anatomy and Cell Biology, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA.
Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, California, USA.

BACKGROUND: Dental pulp stem cells help maintain dental tissue homeostasis and have strong potential for tissue regeneration.

METHODS: The authors reviewed the discovery, biology, regulation, and clinical application potential of dental pulp stem cells.

RESULTS: Studies showed that dental pulp stem cells contribute to pulp repair, tissue homeostasis, immune regulation, and regeneration.

CONCLUSIONS: This review showed that dental pulp stem cells have advanced from basic discovery to promising clinical application.

PMID: 32950195
DOI: 10.1016/j.joen.2020.06.027